In this episode, we make anticoagulants simple by breaking them down using the brick and mortar concept of blood clotting. Think of platelets as the bricks and fibrin as the mortar — and learn how anticoagulants and antiplatelets interrupt each step to prevent dangerous clots. We’ll cover Heparin, Warfarin, Aspirin, and Plavix, explaining when to use them, how to monitor them, and what to teach patients. You’ll also master lab values, antidotes, and bleeding precautions while connecting it all to Nclex-style questions and safe nursing practice.
Platelets are the bricks; fibrin (clotting factors) is the mortar — together, they form a clot.
Antiplatelets like Aspirin and Plavix stop platelets from sticking together (affect the bricks).
Anticoagulants like Heparin and Warfarin slow or block clotting factors (affect the mortar).
Heparin: rapid IV/SQ action, monitor aPTT (45–80 sec), antidote = protamine sulfate.
Warfarin: slow oral action, monitor INR (2–3), antidote = vitamin K or Kcentra.
Bleeding precautions: soft toothbrush, electric razor, no IM injections, fall precautions.
hit syndrome: platelet drop with heparin—monitor closely.
Nclex focus: select-all-that-apply questions on bleeding precautions, therapeutic ranges, and antidotes.
Teaching tip: Vitamin K–rich foods lower INR — consistency is key.
Safe practice = understanding both sides of clotting: what builds it and what breaks it down.